Personalizing Brain Stimulation
Our goal is to understand the fundamental principles of human brain plasticity and build trans-diagnostic real-time monitoring platforms for personalized neurotherapeutics.
We use an array of neuroscience methods to better understand the basic principles of how to create change in brain circuits. We use this knowledge to develop more effective treatment strategies for depression and other psychiatric disorders.
Keller et al., Proceedings of the National Academy of Sciences, 2011
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Mental health is central to our well being, our relationships, and to society. Unfortunately, mental healthcare is often applied in a one-size-fits-all manner, cycling through multiple treatments without reference to one’s biology as a guide, leading to reduced efficacy.
To change this, through scientific and ethical rigor we seek to better understand the fundamental principles and develop new tools to quantify 1) how brain circuits interact, 2) how treatments change these circuits, and 3) how these changes map onto clinical symptoms. A deep knowledge of the relationship between brain circuits and symptoms will reduce the stigma around mental health and translate to targeted, personalized, and more effective treatments.
The goal of our laboratory is to develop an environment conducive to team-based learning in order to train the next generation of clinically-informed circuit neuroscientists. We will be recognized for questioning the status quo with rigorous scientific experiments and will make important scientific contributions in understanding how brain stimulation alters neural circuits and behavior.
Corey Keller MD, PhD
Assistant Professor, Psychiatry and Behavioral Sciences, Stanford University
Member, Wu Tsai Neurosciences Institute
Co-founder and former CMO, Alto Neuroscience
Residency, Stanford University
MD and PhD in Neuroscience, Albert Einstein College of Medicine
BS in Electrical and Biomedical Engineering, Tufts University
NIMH R01 (2)
BWF Career Award for Medical Scientists
NIH Director's Early Independence Award DP5
NIMH K23 award (completed)
NIINDS F31 (completed)
Identifying the fundamental principles of human brain plasticity
How does a set of electrical or magnetic impulses change the brain?
Developing novel methods to directly probe the human brain
How can we directly measure brain connectivity in humans?
Journal of Neuroscience 2019
Journal of Neuroscience 2018
Cerebral Cortex 2017
PLoS One 2016
Journal of Neuroscience 2015
Journal of Neuroscience 2013
Proceedings of the National Academy of Sciences 2011
Please reach out if you would like to explore opportunities to join us! We are currently hiring:
More information can be found here
401 Quarry Road, Stanford, CA
Palo Alto VA
3801 Miranda Road, Palo Alto, CA